Menopause, low testosterone and ageing are two things which have always been considered to have a cause and effect relationship. Men who go to the gym regularly and struggle to put on learn muscle may have an underlying testosterone deficiency, check out trtruk.co.uk for more. TRT is a solutions for the ‘Male Menopause’ where the testes reduce production of testosterone by 1% each year from 30 years of age. For a long time, the hot flushes and the sleepless nights were seen to be symptoms of growing older, but now studies have turned these misconceptions on their head.
In two investigations conducted by UCLA, it has been suggested that menopause, and the insomnia that often accompanies it, have been linked with the acceleration of biological aging.
“For decades, scientists have disagreed over whether menopause causes aging or aging causes menopause”, said Steve Horvath, a professor of human genetics and biostatistics at UCLA. “It’s like the chicken or the egg: which came first? Our study is the first to demonstrate that menopause makes you age faster”.
The study compared the relationship between chronological age and biological age by measuring women’s age against a biological clock. The method, which was developed by Hovarth, is widely used as a way of tracking the changes and epigenetic shifts of the genome.
The researchers measured the biological age of cells from blood and saliva inside the cheek, of over 3,000 women to study methylation – a chemical biomarker of cellular aging.
“We discovered that menopause speeds up cellular aging by an average of 6 percent,” said Horvath. “That doesn’t sound like much but it adds up over a woman’s lifespan”.
Further research on over 2,000 women found that women who suffered from insomnia during the change were nearly two years older biologically than those who could sleep through the night.
The study concluded that women who experience menopause earlier, also age at a faster rate than those who go through the menopause at a later age.
Findings of the studies are regarded as significant as cellular aging has been linked to increased risks of developing diseases, such as cancer, dementia and other age-related conditions.
The conclusions of the research further support the case for Hormone Replacement Therapy (HRT), which many women rely on to alleviate the menopausal symptoms.